Neue Studie über die Zusammenarbeit im Bereich der angeborenen Herzfehler bei Erwachsenen

Neue Studie über die Bedeutung der nationalen und internationalen Zusammenarbeit im Bereich der angeborenem Herzfehler bei Erwachsenen: eine Analyse der Forschungsergebnisse


Mai 2015




The determinants of adult congenital heart disease (ACHD) research output are only partially understood. The heterogeneity of ACHD naturally calls for collaborative work; however, limited information exists on the impact of collaboration on academic performance. We aimed to examine the global topology of ACHD research, distribution of research collaboration and its association with cumulative research output.


Methods and results


Based on publications presenting original research between 2005 and 2011, a network analysis was performed quantifying centrality measures and key players in the field of ACHD. In addition, network maps were produced to illustrate the global distribution and interconnected nature of ACHD research. The proportion of collaborative research was 35.6 % overall, with a wide variation between countries (7.1 to 62.8%). The degree of research collaboration, as well as measures of network centrality (betweenness and degree centrality), were statistically associated with cumulative research output independently of national wealth and available workforce. The global ACHD research network was found to be scale-free with a small number of central hubs and a relatively large number of peripheral nodes. In addition, we could identify potentially influential hubs based on cluster analysis and measures of centrality/key player analysis.




Using network analysis methods the current study illustrates the complex and global structures of ACHD research. It suggests that collaboration between research institutions is associated with higher academic output. As a consequence national and international collaboration in ACHD research should be encouraged and the creation of an adequate supporting infrastructure should be further promoted.


This study was supported by a research grant from the EMAH Stiftung Karla Voellm, Krefeld, Germany.


© 2015 Elsevier Ireland Ltd. Published by Elsevier Inc. All rights reserved.

Unsere Förderer:
Robert Bosch Stiftung
Stiftung Stahlwerk Georgsmarienhütte
Hengler Mueller Rechtsanwälte
Verbände und Aktionen:
Bundesverband Deutscher Stiftungen
Robert Bosch Stiftung - Verantwortung Unternehmen